International Journal of Recent Advances in science and technology https://www.ijrast.com/index.php/ijrast <h3>International Journal of Recent Advances in Science and Technology</h3> <p><strong>International Journal of Recent Advances in science and technology (IJRAST)</strong> is an official peer-reviewed journal published quarterly, with a total of 4 issues a year. The journal aims to publish high-quality scientific research in the field of science and technology. Original articles, review articles, short communications, and letters to the editor in science &amp; technology are accepted.</p> <p>All manuscript is first double-blind reviewed by an Editorial Advisory Group with the power to recommend rejection or referral for review by one or more subject referees. Manuscripts from the review may be accepted, returned to the author for revision or rejected. All final decisions on a manuscript are at the Editor's discretion.</p> <p><img src="https://www.ijrast.com/public/site/images/ramandeepsingh/88x31.png" alt="" /><br />This work is licensed under a Creative Commons Attribution 4.0 International License</p> en-US contact.ijrast@gmail.com (Ramandeep Singh) contact.ijrast@gmail.com (Ramandeep Singh) Fri, 21 Aug 2020 05:48:07 +0000 OJS 3.2.1.1 http://blogs.law.harvard.edu/tech/rss 60 Phytochemical Screening and Anti-inflammatory activity of Murraya Koenigii & Ficus Lacor roots in Carrageenan, Histamine and Serotonin induced paw edema in albino Wistar rats https://www.ijrast.com/index.php/ijrast/article/view/54 <p>Objective: To perform the Phytochemical Screening &amp; Anti-inflammatory activity of Murraya Koenigii &amp; Ficus Lacor roots in Albino Wistar rats.</p> <p>Methods: The different Pharmacognostical parameters were evaluated as per standard procedure. The crude drug was evaluated for organoleptic properties shape, size, color, odor, taste. Preliminary Phytochemical Screening was carried out &amp; finally Anti-inflammatory activity was evaluated by adopting different methods.</p> <p>Results: The extracts showed a marked Anti-inflammatory effect. The FLET fraction from Ficus lacor aerial roots showed maximum inhibition (75%) of Carrageenan induced edema (Table 3.12B), followed by FLPE and MKCF from Murraya koenigii roots (74 % and 70% approx) (p &lt;0.001 for all). The inhibition of inflammation was comparable for all the fractions for any change in extent &amp; percentage of inhibition at 30 min, 1hr, 2hr and 3hr. The anti-inflammatory effect induced via indomethacin gradually increased and reached at higher level (80.8%) after 3 hrs. It was maintained up to six hours. For, MKPE the inhibition was observed to be maximum at the end of 2 hrs and then tapered. MKEA, FLEA and FLCF showed minimum response that was constant throughout and insignificant. MKPE was slightly significant (55.1 %, p&lt;0.05) which was more effective.</p> <p>Conclusion: The results of the study indicate that the extract of Murraya koenigii roots and Ficus lacor possesses strong Anti-inflammatory activity. This study also describes therapeutic effect of Murraya koenigii roots and Ficus lacor aerial roots in inflammation and arthritis which will give a new direction for the future scientific research.</p> Kapil Dev Pandey, Yogendra Singh, Naresh Khatri, Narendra Singh Copyright (c) 2020 International Journal of Recent Advances in science and technology https://www.ijrast.com/index.php/ijrast/article/view/54 Fri, 21 Aug 2020 00:00:00 +0000